Journal of Liver Cancer

Won Jae Lee

5 Articles

A Case of Hepatocellular Carcinoma With Bile Duct Thrombi Presenting Obstructive Jaundice: Su Rin Shin, Geum-Youn Gwak, Cheol Keun Park, Won Jae Lee, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Won Paik, Byung Chul Yoo; Journal of the Korean Liver Cancer Study Group. 2008;8(1):47-50. Published online June 30, 2008

Abstract PDF: Although invasion into blood vessels, particularly the portal vein, is a common feature of hepatocellular carcinoma (HCC), intrabile duct invasion has been considered rare. HCC with bile duct thrombi is occasionally misdiagnosed as biliary carcinoma or stone, and tends to have a worse clinical course than HCC without bile duct thrombi, probably attributable to the low resectability rate secondary to poor functional reserve caused by obstructive jaundice, and combined major vascular invasion. However, a few data demonstrated that obstructive jaundice aroused an early detection of HCC, leading to a better survival. Herein, we describe a case of HCC with bile duct thrombi, which was diagnosed at an early stage with obstructive jaundice and had a favorable course after surgical resection.

Surgical Removal of Needle-Tract Seeding in Hepatocellular Carcinoma: A Report of Two Cases: Soo Ah Kim, Won Jae Lee, Seung Hoon Kim, Hyo Keun Lim; Journal of the Korean Liver Cancer Study Group. 2002;2(1):69-72. Published online July 31, 2002

Abstract PDF: We describe two case of needle-tract seeding found in the abdominal wall after performing needle biopsy and radiofrequency ablation in a 56 year-old man and 41-year-old woman with hepatocellular carcinomas. Needle-tract seeding was identified at CT 19 and 14 months after the interventional procedures, respectively. Surgical removal was undergone successfully in both patients

Hepatocellular Carcinoma Arising in Hepatic Adenomatosis: Sun-Young Lee, Moon Seok Choi, Joon Hyoek Lee, Kwang Cheol Koh, Seung Woon Paik, Won Jae Lee; Journal of the Korean Liver Cancer Study Group. 2002;2(1):80-82. Published online July 31, 2002

Abstract PDF: Hepatic adenomatosis is a disease entity composed of more than 10 adenomas within a normal liver parenchyme. Adenomas in hepatic adenomatosis impare liver function such as ALP and GGT, and also increase the risk of carcinoma and hemorrhage. Imaging study plays important role in diagnosis. And although there is a high risk of hemorrhage via biopsy, it is important to confirm the malignant component and differentiate from metastatic disease or multifocal hepatocellular carcinoma. The treatment is usually lobectomy or embolization of the arterial supply to the largest tumor. A 28 year-old-man visited our mstitute because of abnormal findings in routine liver function test. On CT finding, there were 15 hepatic masses. The largest one was exceeding 9 cm locating in the right lobe. Although the largest mass revealed hepatocellular carcinoma through biopsy, other 14 nodules were all adenomas. Right lobectomy was done. After 2 months from the operation, transarterial chemoembolization was done for the two times thereafter. He is on regular follow-up at outpatient department without evidence of recurrence.

5 Case Reports of Hepatic Epithelioid Hemangioendothelioma: Beom Jin Kim, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Won Jae Lee, Cheol Keun Park; Journal of the Korean Liver Cancer Study Group. 2002;2(1):88-92. Published online July 31, 2002

Abstract PDF: Background/Aims: Hepatic epithelioid hemangioendothelioma is a rare vascular tumor of the liver. It poses special difficulties for clinicians in its diagnosis and treatment. Its clinical course and prognosis are variable. However, there are only a few case reports in Korea. Therefore we studied the clinical characteristics of hepatic epithelioid hemangioendothelioma which had been diagnosed and treated in our hospital. Methods: The clinical, radiological and pathologic characteristics of 5 cases were reviewed retrospectively. Results: The patients included three males and two females and the mean age was 48.6 years. The chief complaints were asymptomatic (4 cases) or abdominal pain (1 case). Blood chemistry test was abnormal in one patient. CT scan showed multiple hypoattenuated masses in the periphery of the liver. Ultrasound-guided liver biopsy was done for all cases. On the immunohistochemical staining, factor Ⅷ was positive in three cases, CD34 was positive in three cases. In the treatment, conservative management was done for all cases. There was no significant disease progression during the follow-up period of 25.4 months. Conclusions: Hepatic epithelioid hemangioendothelioma presents nonspecific symptoms and shows low grade malignancy and slow disease progression. Radiologic studies such as CT with biopsy may give the clue for the diagnosis.

Undifferentiated Embryomal Sarcoma: A Case Report: Jin Young Na, Won Jae Lee, Seung Hoon Kim, Hyo Keun Lim; Journal of the Korean Liver Cancer Study Group. 2002;2(1):93-95. Published online July 31, 2002

Abstract PDF: A 60-year-old woman who admitted to our institute due to general malaise for 1 year was found to have a huge hepatic mass at ultrasound and CT. The hepatic tumor was histologically confirmed to be undifferentiated embryonal sarcoma by means of percutaneous needle biopsy under ultrasound guidance. Though this malignant hepatic tumor usually occurs in children and young adults, we report a case of undifferentiated embryonal sarcoma that occurred in an old woman.